NFL Running Backs
| Name | Team | Carries | Yards | Avg. | TDs |
| Clinton Portis | Washington Redskins | 325 | 1,262 | 3.90 | 11 |
| Edgerrin James | Arizona Cardinals | 324 | 1,222 | 3.80 | 7 |
| Willie Parker | Pittsburgh Steelers | 321 | 1,316 | 4.10 | 2 |
| LaDainian Tomlinson | San Diego Chargers | 315 | 1,474 | 4.70 | 15 |
| Thomas Jones | New York Jets | 310 | 1,119 | 3.60 | 1 |
| LenDale White | Tennessee Titans | 303 | 1,110 | 3.70 | 7 |
| Jamal Lewis | Cleveland Browns | 298 | 1,304 | 4.40 | 9 |
| Willis McGahee | Baltimore Ravens | 294 | 1,207 | 4.10 | 7 |
| Marshawn Lynch | Buffalo Bills | 280 | 1,115 | 4.00 | 7 |
| Brian Westbrook | Philadelphia Eagles | 278 | 1,333 | 4.80 | 7 |
| Joseph Addai | Indianapolis Colts | 261 | 1,072 | 4.10 | 12 |
| Frank Gore | San Francisco 49ers | 260 | 1,102 | 4.20 | 5 |
| DeShaun Foster | San Francisco 49ers | 247 | 876 | 3.50 | 3 |
| Adrian Peterson | Minnesota Vikings | 238 | 1,341 | 5.60 | 12 |
| Steven Jackson | St. Louis Rams | 237 | 1,002 | 4.20 | 5 |
| Warrick Dunn | Tampa Bay Buccaneers | 227 | 720 | 3.20 | 4 |
| Fred Taylor | Jacksonville Jaguars | 223 | 1,202 | 5.40 | 5 |
| Justin Fargas | Oakland Raiders | 222 | 1,009 | 4.50 | 4 |
| Earnest Graham | Tampa Bay Buccaneers | 222 | 898 | 4.00 | 10 |
| Shaun Alexander | Seattle Seahawks | 207 | 716 | 3.50 | 4 |
| Marion Barber | Dallas Cowboys | 204 | 975 | 4.80 | 10 |
| Brandon Jacobs | New York Giants | 202 | 1,009 | 5.00 | 4 |
| Cedric Benson | Chicago Bears | 196 | 674 | 3.40 | 4 |
| Ron Dayne | Houston Texans | 194 | 773 | 4.00 | 6 |
| Ryan Grant | Green Bay Packers | 188 | 956 | 5.10 | 8 |
| Laurence Maroney | New England Patriots | 185 | 835 | 4.50 | 6 |
| Kenny Watson | Cincinnati Bengals | 178 | 763 | 4.30 | 7 |
| Rudi Johnson | Cincinnati Bengals | 170 | 497 | 2.90 | 3 |
| Travis Henry | Denver Broncos | 167 | 691 | 4.10 | 4 |
| Maurice Jones-Drew | Jacksonville Jaguars | 167 | 768 | 4.60 | 9 |
| Julius Jones | Seattle Seahawks | 164 | 588 | 3.60 | 2 |
| Larry Johnson | Kansas City Chiefs | 158 | 559 | 3.50 | 3 |
| Reggie Bush | New Orleans Saints | 157 | 581 | 3.70 | 4 |
| Chester Taylor | Minnesota Vikings | 157 | 844 | 5.40 | 7 |
| Kevin Jones | Detroit Lions | 153 | 581 | 3.80 | 8 |
| Adrian Peterson | Chicago Bears | 151 | 510 | 3.40 | 3 |
| LaMont Jordan | Oakland Raiders | 144 | 549 | 3.80 | 3 |
| DeAngelo Williams | Carolina Panthers | 144 | 717 | 5.00 | 4 |
| Maurice Morris | Seattle Seahawks | 140 | 628 | 4.50 | 4 |
| Selvin Young | Denver Broncos | 140 | 729 | 5.20 | 1 |
| Jesse Chatman | New York Jets | 128 | 515 | 4.00 | 1 |
| Derrick Ward | New York Giants | 125 | 602 | 4.80 | 3 |
| Kenton Keith | Indianapolis Colts | 121 | 533 | 4.40 | 3 |
| Ronnie Brown | Miami Dolphins | 119 | 602 | 5.10 | 4 |
| Aaron Stecker | New Orleans Saints | 115 | 448 | 3.90 | 5 |
| Kolby Smith | Kansas City Chiefs | 112 | 407 | 3.60 | 2 |
| Najeh Davenport | Pittsburgh Steelers | 107 | 499 | 4.70 | 5 |
| Jerious Norwood | Atlanta Falcons | 103 | 613 | 6.00 | 1 |
| Chris Brown | Houston Texans | 102 | 462 | 4.50 | 5 |
| Ladell Betts | Washington Redskins | 93 | 335 | 3.60 | 1 |
| Brian Leonard | St. Louis Rams | 86 | 303 | 3.50 | 0 |
| Reuben Droughns | New York Giants | 85 | 275 | 3.20 | 6 |
| Sammy Morris | New England Patriots | 85 | 384 | 4.50 | 3 |
| Brandon Jackson | Green Bay Packers | 75 | 267 | 3.60 | 1 |
| Dominic Rhodes | Oakland Raiders | 75 | 302 | 4.00 | 1 |
| Musa Smith | Baltimore Ravens | 75 | 264 | 3.50 | 2 |
| Michael Turner | Atlanta Falcons | 71 | 316 | 4.50 | 1 |
| Leon Washington | New York Jets | 71 | 353 | 5.00 | 3 |
| Ahman Green | Houston Texans | 70 | 260 | 3.70 | 2 |
| Michael Pittman | Tampa Bay Buccaneers | 68 | 286 | 4.20 | 0 |
| T.J. Duckett | Seattle Seahawks | 65 | 335 | 5.20 | 3 |
| Correll Buckhalter | Philadelphia Eagles | 62 | 313 | 5.00 | 4 |
| Kevin Faulk | New England Patriots | 62 | 265 | 4.30 | 0 |
| Michael Bennett | Tampa Bay Buccaneers | 61 | 241 | 4.00 | 1 |
| Jason Wright | Cleveland Browns | 60 | 277 | 4.60 | 1 |
| Fred Jackson | Buffalo Bills | 58 | 300 | 5.20 | 0 |
| Darius Walker | Houston Texans | 58 | 264 | 4.60 | 1 |
| Cadillac Williams | Tampa Bay Buccaneers | 54 | 208 | 3.90 | 3 |
| Samkon Gado | Miami Dolphins | 53 | 150 | 2.80 | 4 |
| Pierre Thomas | New Orleans Saints | 52 | 252 | 4.80 | 1 |
| DeShawn Wynn | Green Bay Packers | 50 | 203 | 4.10 | 4 |
| Tatum Bell | Detroit Lions | 44 | 182 | 4.10 | 1 |
| Andre Hall | Denver Broncos | 44 | 216 | 4.90 | 2 |
| Antonio Pittman | St. Louis Rams | 38 | 139 | 3.70 | 0 |
| Darren Sproles | San Diego Chargers | 37 | 164 | 4.40 | 2 |
| Anthony Thomas | Buffalo Bills | 36 | 89 | 2.50 | 0 |
| Kyle Eckel | New England Patriots | 33 | 90 | 2.70 | 2 |
| Chris Henry | Tennessee Titans | 31 | 119 | 3.80 | 2 |
| Garrett Wolfe | Chicago Bears | 31 | 85 | 2.70 | 0 |
| Clifton Dawson | Indianapolis Colts | 30 | 64 | 2.10 | 1 |
| Vernand Morency | Green Bay Packers | 29 | 108 | 3.70 | 0 |
| Dwayne Wright | Buffalo Bills | 29 | 94 | 3.20 | 0 |
| Lorenzo Booker | Philadelphia Eagles | 28 | 125 | 4.50 | 0 |
| J.J. Arrington | Arizona Cardinals | 26 | 78 | 3.00 | 0 |
| Michael Robinson | San Francisco 49ers | 26 | 121 | 4.70 | 0 |
| Deuce McAllister | New Orleans Saints | 24 | 92 | 3.80 | 0 |
| Ahmad Bradshaw | New York Giants | 23 | 190 | 8.30 | 1 |
| Jerome Harrison | Cleveland Browns | 23 | 142 | 6.20 | 0 |
| DeDe Dorsey | Cincinnati Bengals | 21 | 183 | 8.70 | 0 |
| Maurice Hicks | Minnesota Vikings | 21 | 117 | 5.60 | 1 |
| Adimchinobe Echemandu | Oakland Raiders | 20 | 85 | 4.20 | 0 |
| Mewelde Moore | Pittsburgh Steelers | 20 | 113 | 5.60 | 0 |
| Travis Minor | St. Louis Rams | 17 | 68 | 4.00 | 0 |
| Mike Anderson | Baltimore Ravens | 15 | 62 | 4.10 | 0 |
| Patrick Cobbs | Miami Dolphins | 15 | 47 | 3.10 | 1 |
| Marcel Shipp | Arizona Cardinals | 15 | 41 | 2.70 | 1 |
| Jackie Battle | Kansas City Chiefs | 14 | 47 | 3.40 | 1 |
| Tyson Thompson | Dallas Cowboys | 14 | 54 | 3.90 | 0 |
| Jason Snelling | Atlanta Falcons | 13 | 43 | 3.30 | 1 |
| LaBrandon Toefield | Carolina Panthers | 13 | 27 | 2.10 | 1 |
| Cory Ross | Baltimore Ravens | 12 | 72 | 6.00 | 1 |
| Aveion Cason | Detroit Lions | 11 | 38 | 3.50 | 0 |
| Tony Hunt | Philadelphia Eagles | 10 | 16 | 1.60 | 1 |
| Brian Calhoun | Detroit Lions | 7 | 35 | 5.00 | 0 |
| Tony Richardson | New York Jets | 7 | 13 | 1.90 | 0 |
| Gary Russell | Pittsburgh Steelers | 7 | 21 | 3.00 | 0 |
| Mike Bell | Denver Broncos | 6 | 3 | 0.50 | 0 |
| Ricky Williams | Miami Dolphins | 6 | 15 | 2.50 | 0 |
| Luke Lawton | Indianapolis Colts | 5 | 13 | 2.60 | 0 |
| Artose Pinner | Detroit Lions | 5 | 46 | 9.20 | 0 |
| Thomas Tapeh | Minnesota Vikings | 5 | 18 | 3.60 | 0 |
| Alex Haynes | Carolina Panthers | 3 | 3 | 1.00 | 0 |
| Rock Cartwright | Washington Redskins | 2 | 0 | 0.00 | 0 |
| Kenneth Darby | Tampa Bay Buccaneers | 2 | 9 | 4.50 | 0 |
| Chris Barclay | New Orleans Saints | 1 | 3 | 3.00 | 0 |
| Rich Alexis | St. Louis Rams | 0 | -- | -0.00 | 0 |
| Charles Ali | Cleveland Browns | 0 | -- | -0.00 | 0 |
| Steve Baylark | Arizona Cardinals | 0 | -- | -0.00 | 0 |
| Arliss Beach | Houston Texans | 0 | -- | -0.00 | 0 |
| DeCori Birmingham | Carolina Panthers | 0 | -- | -0.00 | 0 |
| Cory Boyd | Tampa Bay Buccaneers | 0 | -- | -0.00 | 0 |
| Nehemiah Broughton | Washington Redskins | 0 | -- | -0.00 | 0 |
| Thomas Brown | Atlanta Falcons | 0 | -- | -0.00 | 0 |
| Eldra Buckley | San Diego Chargers | 0 | -- | -0.00 | 0 |
| Dan Burks | Cincinnati Bengals | 0 | -- | -0.00 | 0 |
| Michael Bush | Oakland Raiders | 0 | -- | -0.00 | 0 |
| Jamaal Charles | Kansas City Chiefs | 0 | -- | -0.00 | 0 |
| Tashard Choice | Dallas Cowboys | 0 | -- | -0.00 | 0 |
| Thomas Clayton | San Francisco 49ers | 0 | -- | -0.00 | 0 |
| Alonzo Coleman | Dallas Cowboys | 0 | -- | -0.00 | 0 |
| Casey Cramer | Tennessee Titans | 0 | -- | -0.00 | 0 |
| Ronnie Cruz | Dallas Cowboys | 0 | -- | -0.00 | 0 |
| Dan Curran | Seattle Seahawks | 0 | -- | -0.00 | 0 |
| P.J. Daniels | Baltimore Ravens | 0 | -- | -0.00 | 0 |
| Jason Davis | Philadelphia Eagles | 0 | -- | -0.00 | 0 |
| Robert Douglas | New York Giants | 0 | -- | -0.00 | 0 |
| Kevin Dudley | New Orleans Saints | 0 | -- | -0.00 | 0 |
| Jonathan Evans | Buffalo Bills | 0 | -- | -0.00 | 0 |
| Troy Fleming | Carolina Panthers | 0 | -- | -0.00 | 0 |
| Justin Forsett | Seattle Seahawks | 0 | -- | -0.00 | 0 |
| Matt Forte | Chicago Bears | 0 | -- | -0.00 | 0 |
| Quinton Ganther | Tennessee Titans | 0 | -- | -0.00 | 0 |
| Nick Goings | Carolina Panthers | 0 | -- | -0.00 | 0 |
| Justin Green | Baltimore Ravens | 0 | -- | -0.00 | 0 |
| Tyronne Gross | San Diego Chargers | 0 | -- | -0.00 | 0 |
| Justise Hairston | Indianapolis Colts | 0 | -- | -0.00 | 0 |
| Kay-Jay Harris | New York Giants | 0 | -- | -0.00 | 0 |
| Mike Hart | Indianapolis Colts | 0 | -- | -0.00 | 0 |
| Verron Haynes | Pittsburgh Steelers | 0 | -- | -0.00 | 0 |
| Noah Herron | Green Bay Packers | 0 | -- | -0.00 | 0 |
| Tim Hightower | Arizona Cardinals | 0 | -- | -0.00 | 0 |
| Lex Hilliard | Miami Dolphins | 0 | -- | -0.00 | 0 |
| Oliver Hoyte | Kansas City Chiefs | 0 | -- | -0.00 | 0 |
| Kenny Irons | Cincinnati Bengals | 0 | -- | -0.00 | 0 |
| Chris Johnson | Tennessee Titans | 0 | -- | -0.00 | 0 |
| Felix Jones | Dallas Cowboys | 0 | -- | -0.00 | 0 |
| John Kuhn | Green Bay Packers | 0 | -- | -0.00 | 0 |
| Billy Latsko | Pittsburgh Steelers | 0 | -- | -0.00 | 0 |
| ReShard Lee | Oakland Raiders | 0 | -- | -0.00 | 0 |
| Reno Mahe | Philadelphia Eagles | 0 | -- | -0.00 | 0 |
| Chris Manderino | Kansas City Chiefs | 0 | -- | -0.00 | 0 |
| Marcus Mason | Washington Redskins | 0 | -- | -0.00 | 0 |
| Darren McFadden | Oakland Raiders | 0 | -- | -0.00 | 0 |
| Corey McIntyre | Atlanta Falcons | 0 | -- | -0.00 | 0 |
| Rashard Mendenhall | Pittsburgh Steelers | 0 | -- | -0.00 | 0 |
| Ryan Moats | Philadelphia Eagles | 0 | -- | -0.00 | 0 |
| Xavier Omon | Buffalo Bills | 0 | -- | -0.00 | 0 |
| Montell Owens | Jacksonville Jaguars | 0 | -- | -0.00 | 0 |
| Jalen Parmele | Miami Dolphins | 0 | -- | -0.00 | 0 |
| Allen Patrick | Baltimore Ravens | 0 | -- | -0.00 | 0 |
| Alvin Pearman | Seattle Seahawks | 0 | -- | -0.00 | 0 |
| Chris Perry | Cincinnati Bengals | 0 | -- | -0.00 | 0 |
| Lousaka Polite | Chicago Bears | 0 | -- | -0.00 | 0 |
| P.J. Pope | Chicago Bears | 0 | -- | -0.00 | 0 |
| Ryan Powdrell | Green Bay Packers | 0 | -- | -0.00 | 0 |
| Germaine Race | San Diego Chargers | 0 | -- | -0.00 | 0 |
| Ray Rice | Baltimore Ravens | 0 | -- | -0.00 | 0 |
| J.D. Runnels | Chicago Bears | 0 | -- | -0.00 | 0 |
| B.J. Sams | Kansas City Chiefs | 0 | -- | -0.00 | 0 |
| Pete Schmitt | Washington Redskins | 0 | -- | -0.00 | 0 |
| Josh Scobey | Seattle Seahawks | 0 | 0 | 0.00 | 0 |
| Eric Shelton | Washington Redskins | 0 | -- | -0.00 | 0 |
| Steve Slaton | Houston Texans | 0 | -- | -0.00 | 0 |
| Kevin Smith | Detroit Lions | 0 | -- | -0.00 | 0 |
| Paul Smith | Denver Broncos | 0 | -- | -0.00 | 0 |
| Jonathan Stewart | Carolina Panthers | 0 | -- | -0.00 | 0 |
| Byron Storer | Tampa Bay Buccaneers | 0 | -- | -0.00 | 0 |
| Chris Taylor | Houston Texans | 0 | -- | -0.00 | 0 |
| D.D. Terry | Jacksonville Jaguars | 0 | -- | -0.00 | 0 |
| Marcus Thomas | San Diego Chargers | 0 | -- | -0.00 | 0 |
| Ryan Torain | Denver Broncos | 0 | -- | -0.00 | 0 |
| Chris Vincent | Arizona Cardinals | 0 | -- | -0.00 | 0 |
| Justin Vincent | Pittsburgh Steelers | 0 | -- | -0.00 | 0 |
| Danny Ware | New York Giants | 0 | -- | -0.00 | 0 |
| Chauncey Washington | Jacksonville Jaguars | 0 | -- | -0.00 | 0 |
| Russ Weil | St. Louis Rams | 0 | -- | -0.00 | 0 |
| Corey White | Green Bay Packers | 0 | -- | -0.00 | 0 |
| Arkee Whitlock | Minnesota Vikings | 0 | -- | -0.00 | 0 |
| Shaud Williams | Buffalo Bills | 0 | -- | -0.00 | 0 |