NFL Defensive Tackles
| Name | Team | Tackle | Sack | Fumble | Int. |
| Jovan Haye | Tampa Bay Buccaneers | 68 | 6 | 1 | 0 |
| Mike Patterson | Philadelphia Eagles | 67 | 4 | 1 | 0 |
| Haloti Ngata | Baltimore Ravens | 63 | 3 | 1 | 0 |
| Darnell Dockett | Arizona Cardinals | 58 | 9 | 2 | 0 |
| Dewayne Robertson | Denver Broncos | 57 | 4 | 0 | 0 |
| Tony Brown | Tennessee Titans | 52 | 4 | 1 | 0 |
| Domata Peko | Cincinnati Bengals | 52 | 1 | 0 | 0 |
| Chris Hovan | Tampa Bay Buccaneers | 48 | 1 | 0 | 0 |
| Maake Kemoeatu | Carolina Panthers | 46 | 0 | 0 | 0 |
| Jonathan Babineaux | Atlanta Falcons | 44 | 3 | 2 | 0 |
| Cornelius Griffin | Washington Redskins | 42 | 2 | 0 | 0 |
| Vonnie Holliday | Miami Dolphins | 42 | 2 | 1 | 0 |
| Anthony Montgomery | Washington Redskins | 42 | 0 | 0 | 0 |
| Fred Robbins | New York Giants | 42 | 5 | 0 | 0 |
| Dwan Edwards | Baltimore Ravens | 41 | 1 | 0 | 1 |
| Ed Johnson | Indianapolis Colts | 41 | 1 | 1 | 0 |
| Travis Johnson | Houston Texans | 41 | 0 | 0 | 1 |
| Kyle Williams | Buffalo Bills | 41 | 2 | 0 | 0 |
| Albert Haynesworth | Tennessee Titans | 40 | 6 | 0 | 0 |
| Sione Pouha | New York Jets | 40 | 0 | 0 | 0 |
| Ryon Bingham | San Diego Chargers | 39 | 1 | 0 | 0 |
| La'Roi Glover | St. Louis Rams | 39 | 6 | 0 | 0 |
| Ryan Pickett | Green Bay Packers | 39 | 1 | 0 | 0 |
| Shaun Rogers | Cleveland Browns | 39 | 7 | 0 | 1 |
| Jamal Williams | San Diego Chargers | 39 | 0 | 1 | 0 |
| John Henderson | Jacksonville Jaguars | 38 | 2 | 1 | 0 |
| Kris Jenkins | New York Jets | 38 | 2 | 0 | 0 |
| Kevin Williams | Minnesota Vikings | 38 | 3 | 1 | 2 |
| Rodrique Wright | Miami Dolphins | 38 | 1 | 0 | 0 |
| Cory Redding | Detroit Lions | 37 | 1 | 0 | 0 |
| Tommie Harris | Chicago Bears | 36 | 8 | 2 | 0 |
| Rocky Bernard | Seattle Seahawks | 35 | 3 | 0 | 0 |
| Larry Tripplett | Seattle Seahawks | 35 | 1 | 1 | 1 |
| Corey Williams | Cleveland Browns | 35 | 7 | 3 | 1 |
| Bryant Young | San Francisco 49ers | 35 | 6 | 1 | 0 |
| Michael Myers | Cincinnati Bengals | 34 | 1 | 0 | 1 |
| Amobi Okoye | Houston Texans | 32 | 5 | 1 | 0 |
| John Thornton | Cincinnati Bengals | 32 | 1 | 0 | 0 |
| Raheem Brock | Indianapolis Colts | 31 | 2 | 0 | 0 |
| Brodrick Bunkley | Philadelphia Eagles | 31 | 3 | 0 | 0 |
| Justin Bannan | Baltimore Ravens | 30 | 2 | 1 | 0 |
| Clifton Ryan | St. Louis Rams | 30 | 2 | 3 | 0 |
| Damione Lewis | Carolina Panthers | 29 | 3 | 0 | 0 |
| John McCargo | Buffalo Bills | 29 | 2 | 1 | 0 |
| Brandon Mebane | Seattle Seahawks | 29 | 2 | 0 | 0 |
| Montavious Stanley | Atlanta Falcons | 29 | 0 | 0 | 0 |
| Rob Meier | Jacksonville Jaguars | 27 | 4 | 0 | 0 |
| Ron Edwards | Kansas City Chiefs | 26 | 3 | 0 | 0 |
| Alfonso Boone | Kansas City Chiefs | 25 | 1 | 0 | 0 |
| Craig Terrill | Seattle Seahawks | 25 | 0 | 0 | 0 |
| Spencer Johnson | Buffalo Bills | 24 | 3 | 1 | 0 |
| Keyunta Dawson | Indianapolis Colts | 23 | 1 | 1 | 0 |
| Terdell Sands | Oakland Raiders | 23 | 0 | 0 | 0 |
| Mike Montgomery | Green Bay Packers | 22 | 0 | 0 | 0 |
| Langston Moore | Detroit Lions | 22 | 2 | 0 | 0 |
| Marcus Stroud | Buffalo Bills | 22 | 3 | 0 | 0 |
| Gerard Warren | Oakland Raiders | 22 | 4 | 1 | 0 |
| Ronald Fields | San Francisco 49ers | 21 | 1 | 1 | 0 |
| Johnny Jolly | Green Bay Packers | 21 | 1 | 0 | 0 |
| Brandon McKinney | San Diego Chargers | 21 | 0 | 0 | 0 |
| Trey Lewis | Atlanta Falcons | 19 | 0 | 0 | 1 |
| Marcus Thomas | Denver Broncos | 19 | 0 | 1 | 1 |
| Antwan Lake | New Orleans Saints | 18 | 1 | 0 | 0 |
| Quinn Pitcock | Indianapolis Colts | 18 | 1 | 0 | 0 |
| Brian Young | New Orleans Saints | 18 | 3 | 1 | 0 |
| Shaun Cody | Detroit Lions | 17 | 0 | 0 | 1 |
| Darwin Walker | Carolina Panthers | 17 | 1 | 0 | 0 |
| Jeff Zgonina | Houston Texans | 17 | 0 | 0 | 0 |
| Justin Harrell | Green Bay Packers | 16 | 0 | 0 | 0 |
| Anthony Maddox | Houston Texans | 16 | 2 | 0 | 0 |
| Ryan Sims | Tampa Bay Buccaneers | 16 | 1 | 0 | 0 |
| Randy Starks | Miami Dolphins | 16 | 0 | 0 | 0 |
| C.J. Mosley | New York Jets | 15 | 2 | 2 | 0 |
| Nick Eason | Pittsburgh Steelers | 14 | 0 | 0 | 0 |
| Alvin McKinley | Denver Broncos | 14 | 2 | 1 | 0 |
| Greg Peterson | Tampa Bay Buccaneers | 14 | 1 | 0 | 0 |
| Claude Wroten | St. Louis Rams | 13 | 0 | 1 | 0 |
| Colin Cole | Green Bay Packers | 12 | 0 | 0 | 0 |
| Chartric Darby | Detroit Lions | 12 | 0 | 0 | 0 |
| Kedric Golston | Washington Redskins | 11 | 1 | 0 | 0 |
| Jason Jefferson | Buffalo Bills | 11 | 0 | 0 | 0 |
| Tank Johnson | Dallas Cowboys | 11 | 2 | 0 | 0 |
| Derek Landri | Jacksonville Jaguars | 11 | 0 | 0 | 0 |
| Tank Tyler | Kansas City Chiefs | 11 | 0 | 0 | 0 |
| Alan Branch | Arizona Cardinals | 9 | 0 | 0 | 0 |
| Rod Coleman | Atlanta Falcons | 7 | 2 | 1 | 0 |
| Howard Green | Seattle Seahawks | 7 | 0 | 0 | 0 |
| Matt Toeaina | Chicago Bears | 6 | 0 | 0 | 0 |
| Russell Davis | New York Giants | 5 | 0 | 0 | 0 |
| Steven Harris | Denver Broncos | 5 | 0 | 0 | 0 |
| Dan Klecko | Philadelphia Eagles | 5 | 1 | 0 | 0 |
| Tony McDaniel | Jacksonville Jaguars | 5 | 0 | 0 | 0 |
| Chase Page | Miami Dolphins | 5 | 0 | 0 | 0 |
| Lorenzo Alexander | Washington Redskins | 4 | 0 | 0 | 0 |
| Antwon Burton | Cincinnati Bengals | 4 | 0 | 0 | 0 |
| Daniel Muir | Green Bay Packers | 4 | 0 | 0 | 0 |
| James Reed | Kansas City Chiefs | 3 | 0 | 0 | 0 |
| Le Kevin Smith | New England Patriots | 3 | 0 | 0 | 0 |
| Paul Soliai | Miami Dolphins | 3 | 0 | 0 | 0 |
| Santonio Thomas | New England Patriots | 3 | 0 | 0 | 0 |
| Kevin Vickerson | Tennessee Titans | 3 | 0 | 0 | 0 |
| Tim Bulman | Houston Texans | 2 | 0 | 0 | 0 |
| Dusty Dvoracek | Chicago Bears | 2 | 0 | 0 | 0 |
| Jimmy Kennedy | Jacksonville Jaguars | 2 | 0 | 0 | 0 |
| Josh Shaw | Oakland Raiders | 2 | 0 | 0 | 0 |
| Manuel Wright | New York Giants | 2 | 0 | 0 | 0 |
| Kimo von Oelhoffen | Philadelphia Eagles | 2 | 0 | 0 | 0 |
| Jason Ferguson | Miami Dolphins | 1 | 0 | 0 | 0 |
| Gary Gibson | Carolina Panthers | 1 | 0 | 0 | 0 |
| Cedric Killings | Houston Texans | 1 | 0 | 0 | 0 |
| Rashad Moore | Atlanta Falcons | 1 | 0 | 0 | 0 |
| LaJuan Ramsey | Philadelphia Eagles | 1 | 0 | 0 | 0 |
| Titus Adams | Cincinnati Bengals | 0 | 0 | 0 | 0 |
| Kenderick Allen | Minnesota Vikings | 0 | 0 | 0 | 0 |
| Tim Anderson | Atlanta Falcons | 0 | 0 | 0 | 0 |
| Matthias Askew | Washington Redskins | 0 | 0 | 0 | 0 |
| Conrad Bolston | Green Bay Packers | 0 | 0 | 1 | 0 |
| Ryan Boschetti | Washington Redskins | 0 | 0 | 0 | 0 |
| Joe Bradley | Indianapolis Colts | 0 | 0 | 0 | 0 |
| Kareem Brown | New York Jets | 0 | 0 | 0 | 0 |
| Red Bryant | Seattle Seahawks | 0 | 0 | 0 | 0 |
| Jeremy Clark | Philadelphia Eagles | 0 | 0 | 0 | 0 |
| Joe Cohen | San Francisco 49ers | 0 | 0 | 0 | 0 |
| Glenn Dorsey | Kansas City Chiefs | 0 | 0 | 0 | 0 |
| Lionel Dotson | Miami Dolphins | 0 | 0 | 0 | 0 |
| Damane Duckett | San Francisco 49ers | 0 | 0 | 0 | 0 |
| Sedrick Ellis | New Orleans Saints | 0 | 0 | 0 | 0 |
| Atiyyah Ellison | San Francisco 49ers | 0 | 0 | 0 | 0 |
| Zarnell Fitch | Baltimore Ravens | 0 | 0 | 0 | 0 |
| Andre Fluellen | Detroit Lions | 0 | 0 | 0 | 0 |
| Amon Gordon | Baltimore Ravens | 0 | 0 | 0 | 0 |
| Letroy Guion | Minnesota Vikings | 0 | 0 | 0 | 0 |
| Orien Harris | New Orleans Saints | 0 | 0 | 0 | 0 |
| Marcus Harrison | Chicago Bears | 0 | 0 | 0 | 0 |
| Nick Hayden | Carolina Panthers | 0 | 0 | 0 | 0 |
| Keith Jackson | San Diego Chargers | 0 | 0 | 0 | 0 |
| Antonio Johnson | Tennessee Titans | 0 | 0 | 0 | 0 |
| Thomas Johnson | New York Jets | 0 | 0 | 0 | 0 |
| William Joseph | Oakland Raiders | 0 | 0 | 0 | 0 |
| Kenny King | Baltimore Ravens | 0 | 0 | 0 | 0 |
| Ross Kolodziej | Arizona Cardinals | 0 | 0 | 0 | 0 |
| Trevor Laws | Philadelphia Eagles | 0 | 0 | 0 | 0 |
| Rodney Leisle | New York Giants | 0 | 0 | 0 | 0 |
| Louis Leonard | Cleveland Browns | 0 | 0 | 0 | 0 |
| Matt McChesney | New York Jets | 0 | 0 | 0 | 0 |
| Anthony McFarland | Indianapolis Colts | 0 | 0 | 0 | 0 |
| Dre Moore | Tampa Bay Buccaneers | 0 | 0 | 0 | 0 |
| Frank Okam | Houston Texans | 0 | 0 | 0 | 0 |
| J'Vonne Parker | Baltimore Ravens | 0 | 0 | 0 | 0 |
| Scott Paxson | Pittsburgh Steelers | 0 | 0 | 0 | 0 |
| Carlton Powell | Denver Broncos | 0 | 0 | 0 | 0 |
| DeMario Pressley | New Orleans Saints | 0 | 0 | 0 | 0 |
| DelJuan Robinson | Houston Texans | 0 | 0 | 0 | 0 |
| Ahtyba Rubin | Cleveland Browns | 0 | 0 | 0 | 0 |
| Ian Scott | Carolina Panthers | 0 | 0 | 0 | 0 |
| Jason Shirley | Cincinnati Bengals | 0 | 0 | 0 | 0 |
| Junior Siavii | Dallas Cowboys | 0 | 0 | 0 | 0 |
| Pat Sims | Cincinnati Bengals | 0 | 0 | 0 | 0 |
| Kenny Smith | New England Patriots | 0 | 0 | 0 | 0 |
| Isaac Snell | Denver Broncos | 0 | 0 | 0 | 0 |
| Eric Taylor | Tennessee Titans | 0 | 0 | 0 | 0 |
| Marcus Tubbs | Seattle Seahawks | 0 | 0 | 0 | 0 |
| Steve Williams | Carolina Panthers | 0 | 0 | 0 | 0 |